Annotated Bibliography On The Landscape Of Transcription

LANDSCAPE OF TRANSCRIPTION IN HUMAN CELLS INTRODUCTION The Encyclopedia of DNA Elements (ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and gene expression. RNA highlights the sequential output from genomes which gives the genetic information. They define the cells regulatory capabilities by their synthesis, translation, transport, processing, and modification. DNA, RNA and cellular†¦show more content†¦Cytosol and Nucleus) for 15 cell lines that were observed. This project also aims to evaluate the degree of modification of the identified transcript at their 3’ and 5’ termini in the predicament of polyadenylation or 7-methyl guanosine cap. A genes isoform expression limits the boundary of minimalistic expression strategy which results in general behavior of genes to express simultaneous multiple isoforms. The results of gene expression range nearly at ten to twelve expressed isoforms for every gene in every cell line. This study shows that 6% of the entire annotated non-coding and coding gene transcripts are overlapping with small RNAs. Highly specific subcellular positioning is found for both unannotated annotated short RNA. METHODS In this paper, the necessary RNA data set was generated by subcellular fractionation of the 15 cell lines considered to analyse the human transcriptome. Thus isolated RNAs were classified into two categories long (200 nucleotides) and short (200 nucleotides) and the long transcripts were further separated into polyadenylated and non-polyadenylated transcripts. Data set Generation The procedure followed for data set generation in this paper is mentioned below: †¢ 15 cell lines were acquired for the purpose of this experiment. Process of subcellular compartment fractionation was performed on these cell lines, this included complete cells, nucleus and cytosol (seen in

Poetry On Acid By Mark Strands - 855 Words

Poetry On Acid In Mark Strands â€Å"Eating Poetry,† the author tells a story of an altered view of a mundane task, taken with a view not normally experienced by restrained society. Right or wrong as the author’s actions may be, the poet’s description of his interactions is quite engaging. Expressed in three six line stanzas, the writer flows through the highs and lows of an exceptionally intense literary experience. In the first stanza, Strand starts his first line with the usage of intense imagery. â€Å"Ink runs from the corners of my mouth.† His usage of imagery grabs the reader’s attention and has us immediately wondering why ink is coming from the corners of his mouth. Ink is such an odd thing for someone to have coming from their mouth, and with that one line Strand has made us long to read more. Ink is also traditionally highly toxic, suggesting the writer may have a wish to die a slow, agonizing death. The second line talks about how happy he is, seemingly in conflict with the first line. This portrays that he enjoys eating ink and is rather happy with himself, as maddeningly illogical as this may be. Line three is an example of a metaphor. We learn that the reason he has ink in his mouth is because he was eating poetry. Reality seems to be at odds with what the writer is experiencing, as there would be no way for the ink to still be liquid. Perhaps the sanity of the writ er is in question, and it could be that as he reads the lines of verse he is merely imagining them asShow MoreRelatedAn Assessment of the Impact of Corporate Social Responsibility on Nigerian Society: the Examples of Banking and Communication Industries18990 Words   |  76 Pagesand modern business must think beyond profit maximization toward being at least socially responsible to its society. Today’s heightened interest in the role of business in society has been promoted by increased sensitivity to the 018 Univers. J. Mark. Bus. Res. awareness of environmental and ethical issues. It means our society has become increasingly concerned that greater influence and progress by firms has not been accompanied by equal effort and desire in addressing important social issuesRead MoreOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 Pagesfamily ties in many societies divided nations and communities and isolated individuals to an extent unparalleled in recorded human history. For teachers, in particular, the challenge of weaving together in meaningful ways the seemingly disparate strands of global history in the twentieth century has often led to its neglect. The fact that the most recent phase of the human experience is usually covered only at the end of a multiterm sequence of world history units has meant that it often ends

Bartleby the Scrivener by Herman Melville Essay Example For Students

Bartleby the Scrivener by Herman Melville Essay Herman Melvilles Bartleby the Scrivener is perhaps more relevant today than when he wrote it in 1853. Bartleby is the account of a talented young scrivener who possesses great talent and potential in his career of duplicating and composing documents. The tale takes us to the upscale Wall Street area of New York City, among the buildings and law offices of the city. The young Bartleby is thrown into the typical office drudgery associated with the type of employment he was seeking. The theme of the story questions why we do, what we do, when we go to work. Also the question of why do we feel certain things are just expected of oneself when we choose to enter employment. When Bartleby took the job of a scrivener it was understood that in addition to recording documents, one also is responsible for the editing and proofreading of their own and others work. However, Bartleby had different expectations for himself and his work. Bartlebys behavior questions all that is thought to be universal behavior while at work. Bartleby worked very hard, never taking breaks or even going home. These aspects of Bartleby were viewed as peculiar by his superior and coworkers, but were not undesirable traits. Bartleby also kept to himself most of the time, and did not get involved with office politics or affairs. Like many new employees, Bartleby had a small shared office near the boss so that he could be monitored. A comparison to life by todays office employees trapped in small cubicles could be made. The feeling of privacy is not there, and one could almost feel overwhelmed with only with their work and a small desk. These conditions may have weighed heavily on Bartleby, causing him to not feel very sociable with the others in the office. The life of drudgery as a scrivener grew weary on Bartleby. The odd behavior expressed by Bartleby continued until one day in a act of rebellion he said the words; I would prefer not to. He was referring to the request by his boss the edit his copy. The boss, shocked by this insubordinate behavior and politely asked again, and drew the same response from Bartleby; I would prefer not to. His boss assumed this was a temporary problem with Bartleby and assumed that it would pass in a day or so. His coworkers viewed his action as very odd, and even suggested as loony by one worker. His phrase now consumed every conversation he had with those in the office. His standard response to a request by someone in his office was; I would prefer not to. These words of defiance eventually led to Bartlebys dismissal from his job, and when asked to leave he refused to. This eventually led to his boss being forced to abandon his office in that building and move to another. His boss felt this would end all of his problems with Bartleby and he could go on with his life and business. However, Bartleby could not leave his mind. He was puzzled by the entire situation. The phrase, I would prefer not to., is not accepted in the workplace of then or today. It is understood that while we are at work certain things are expected of you, regardless of what you would rather do. When Bartleby spoke those words he went against all that is assumed by being employed. Bartleby carefully chose his words when being defiant. If he would have simply said no, it would be viewed as plain ignorance. However, the phrase; I would prefer not to. implies that he had put thought into his response and has reason to be defiant.

Integrated Marketing Communications for Battery - MyAssignmenthelp

Question: Discuss about theIntegrated Marketing Communications for Samsung Battery. Answer: Background of Task The Samsung battery crisis started in Australia due to which a number of people faced issues and difficulties (Essany, 2012). The battery time was too limited. In order to solve this issues, Samsung launched a campaign for recalling. The market share of Samsung declined significantly in Australia. For this purpose, Samsung launched an offer according to which it will replace, refund or repair all notes in Australia. However, this campaign did not provide significant results. The market of next innovative product of Samsung also impacted severely. In this report, a marketing campaign for solving this issues and regaining lost market share will be explained in detail. It will be highlighted that how new product can compensate this loss and regain the lost market share. Strategy Statement The name of this campaign is Next is State-of-the-art and marvelous. For purpose of regaining the lost market share and to handle the crisis of battery products, this campaign will be launched in Australia (Zurita, 2013). The strategy statement of this campaign is Whether it is an innovative product, an inspirational communication impression or an energizing style to unifying, we endeavor to support you [Australian Residents] make an obliging negotiation thats actually enhance collaboration. All we organize designed creatively to enable and stimulate you to make longer period communication with loved ones, and most essentially, to take advantage of technology by this technological advancement. Samsung Brand Positioning Samsung is collection of steeliness and expertise for new official, through its marvelous connection attributes and competitive design. The positioning statement of Samsun declares its distinction from other providers of mobile phones. In the domestic market of Australia where countless selection prosper, lustrous facade design of Samsung, escorted through its assortment of features of soft and hard, purify it a prime buying for the youth, scientifically modernized experts. The company struggles to shelter complete market of mobile and smartphones, is currently one of developing and growing global mobile corporations. In Australia, the company came up through innovative concepts to become additionally customer-oriented (Gillin, 2009). Source: https://www.labbrand.com/brandsource/issue-article/brand-positioning-strategies-rising-chinese-smartphone-brands The Samsung possesses exceptional marketing share. The above diagram indicates the brand positioning in detail. The company is providing innovative and differentiated products and services. Its core differentiating aspect is superior and rare designs. Objectives of the Message The core objective of this marketing campaign is to recapture the lost market share of Samsung in Australian market. The new commodity will offer exceptional battery timing along with diverse unique and remarkable features. This product will significantly fulfill the basic connectivity requirements of the target audience. The audience of this message will be provided an innovative product, an inspirational communication impression or an energizing style to unifying. The main outcome is to enhance and boost the communication and connectivity level of Australian people by providing enduring battery timing and innovative features. The core objective of this message is to recapture the lost market share and attract new target market (Bruner Anand 2000). Target Audience The target audience of this campaign will be professionals and experts people. ON the other hand, the residents of Australia are main target market of this campaign. According to geographic segmentation, Australia is targeted. According to demographic segmentation, all males and females are target audience. These individuals are highly qualified and business experts. According to psychographic segmentation, the people belong to upper and middle classes will be targeted. These individual pay more attention in quality and features as compared to price and cost. The excellence of commodity in each aspect is required such as designing, innovative features, availability of internet, long battery timing and connectivity features (Kim, 2013) Current Feelings of Target Audience Currently target market has negative feeling about the performance of Samsung mobiles after battery crisis. They think that next product of Samsung will be influenced negatively as well. In previous campaign, the company said that all affected customers will be compensated. However, target audience thinks that company cannot recover their loss and wastage of financed. However, it is expected that the feeling of Australian people will change and they will prefer this brand excellently. It is expected that company will recapture 15% market share by introducing this innovative products. It is expected that more than 20000 cases of new mobile phone will be sold in 1st year after inauguration (Dilger, 2015). Various Delivery Media Types The new commodity will be launched with an Integrated Marketing Communications campaign in Australia. This campaign might attract the customers who utilize smart phones as well as appreciate possessing the up-to-the-minute technology. The below mentioned advertising media tools will be used: Advertising In order to make brand consciousness, the TV advertisement is designed. The advertising agency of Samsung will launch new campaign in this year in Australia. The video ad shows how exhilarating and thrilling new product of Samsung is and its innovative features. The people can be seen in ads whose batteries of cell phones finish at most awful moments. Internet Marketing In this digital and globalized era, the successful results of a campaign cannot be achieved without online and internet marketing. The banners will be posted on pages of Facebook and YouTube. These are biggest and most essential social sites that provide exceptional marketing results. The ads will be posted on Facebook, Twitter, YouTube and website of the company (Ovide Wakabayashi 2015). Sales Promotions In order to appeal new target market, the persons who purchase an innovative Samsung phone will be provided a pack of bonus. On the other hand, the old mobiles with poor battery experience will be exchanged with new ones. 20% discount will be offered to first 1000 customers of new mobile. On returning old ones, the half price will be repaid by company (Campbell, 2015). Direct Marketing and PR Public relations are considered essential for promoting product. The celebrity endorsement will be used. A celebrity presenting new cellphone in front of millions of people is best. For direct marketing, the company will offer online and offline services. After sale services will be offered. The new product will be launched in a ceremony in which well-known celebrities and individuals will be invited. References Campbell, M. 2015. Samsung profits drop as mobile arm suffers 37.6% crash in Q2. AppleInsider. Retrieved from: https://appleinsider.com/articles/15/07/29/samsung-profits-drop-asmobile-arm-suffers-376-profit-crash-in-q2 Dilger, D.E. 2015. Samsung Mobile smartphone profits decline; unit sales to shrink for 2015. AppleInsider. Retrieved from: https://appleinsider.com/articles/15/10/29/samsung-mobilesmartphone-profits-decline-unit-sales-to-shrink-for-2015 Kim, M. 2013. Samsung's marketing splurge doesn't always bring bang-forbuck. Reuters. Retrieved from: https://www.reuters.com/article/us-samsung-marketingidUSBRE9AQ18720131127 Bruner, G. C. Anand, K. 2000. Web commercials and advertising hierarchy-of-effects. Journal of Advertising Research, 40 (1/2), p. 35-42 Gillin, P. 2009. Secrets of social media marketing: how to use online conversations and customer communities to turbo-charge your business. Fresno, CA: Quill Driver Books Essany, M. 2012. Target Touts Big 2013 focus on Mobile Marketing for Hispanic Community. Retrieved from: https://www.mobilemarketingwatch.com/target-toutsbig-2013-focus-on-mobile-marketing-for-hispaniccommunity-27662/ Zurita, A. 2013. Mobile Banking in Mexico: An Everyday Reality. Reach Hispanic. Retrieved from: https://reachhispanic.com/2013/08/13/mobile-banking-inmexico-an-everyday-reality/ Ovide, S., Wakabayashi, D. 2015. Apples share of smartphone industrys profits soars to 92%. The Wall Street Journal. Retrieved from: https://www.wsj.com/articles/apples-share-ofsmartphone-industrys-profits-soars-to-92-1436727458