Annotated Bibliography On The Landscape Of Transcription

LANDSCAPE OF TRANSCRIPTION IN HUMAN CELLS INTRODUCTION The Encyclopedia of DNA Elements (ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and gene expression. RNA highlights the sequential output from genomes which gives the genetic information. They define the cells regulatory capabilities by their synthesis, translation, transport, processing, and modification. DNA, RNA and cellular†¦show more content†¦Cytosol and Nucleus) for 15 cell lines that were observed. This project also aims to evaluate the degree of modification of the identified transcript at their 3’ and 5’ termini in the predicament of polyadenylation or 7-methyl guanosine cap. A genes isoform expression limits the boundary of minimalistic expression strategy which results in general behavior of genes to express simultaneous multiple isoforms. The results of gene expression range nearly at ten to twelve expressed isoforms for every gene in every cell line. This study shows that 6% of the entire annotated non-coding and coding gene transcripts are overlapping with small RNAs. Highly specific subcellular positioning is found for both unannotated annotated short RNA. METHODS In this paper, the necessary RNA data set was generated by subcellular fractionation of the 15 cell lines considered to analyse the human transcriptome. Thus isolated RNAs were classified into two categories long (200 nucleotides) and short (200 nucleotides) and the long transcripts were further separated into polyadenylated and non-polyadenylated transcripts. Data set Generation The procedure followed for data set generation in this paper is mentioned below: †¢ 15 cell lines were acquired for the purpose of this experiment. Process of subcellular compartment fractionation was performed on these cell lines, this included complete cells, nucleus and cytosol (seen in

Poetry On Acid By Mark Strands - 855 Words

Poetry On Acid In Mark Strands â€Å"Eating Poetry,† the author tells a story of an altered view of a mundane task, taken with a view not normally experienced by restrained society. Right or wrong as the author’s actions may be, the poet’s description of his interactions is quite engaging. Expressed in three six line stanzas, the writer flows through the highs and lows of an exceptionally intense literary experience. In the first stanza, Strand starts his first line with the usage of intense imagery. â€Å"Ink runs from the corners of my mouth.† His usage of imagery grabs the reader’s attention and has us immediately wondering why ink is coming from the corners of his mouth. Ink is such an odd thing for someone to have coming from their mouth, and with that one line Strand has made us long to read more. Ink is also traditionally highly toxic, suggesting the writer may have a wish to die a slow, agonizing death. The second line talks about how happy he is, seemingly in conflict with the first line. This portrays that he enjoys eating ink and is rather happy with himself, as maddeningly illogical as this may be. Line three is an example of a metaphor. We learn that the reason he has ink in his mouth is because he was eating poetry. Reality seems to be at odds with what the writer is experiencing, as there would be no way for the ink to still be liquid. Perhaps the sanity of the writ er is in question, and it could be that as he reads the lines of verse he is merely imagining them asShow MoreRelatedAn Assessment of the Impact of Corporate Social Responsibility on Nigerian Society: the Examples of Banking and Communication Industries18990 Words   |  76 Pagesand modern business must think beyond profit maximization toward being at least socially responsible to its society. Today’s heightened interest in the role of business in society has been promoted by increased sensitivity to the 018 Univers. J. Mark. Bus. Res. awareness of environmental and ethical issues. It means our society has become increasingly concerned that greater influence and progress by firms has not been accompanied by equal effort and desire in addressing important social issuesRead MoreOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 Pagesfamily ties in many societies divided nations and communities and isolated individuals to an extent unparalleled in recorded human history. For teachers, in particular, the challenge of weaving together in meaningful ways the seemingly disparate strands of global history in the twentieth century has often led to its neglect. The fact that the most recent phase of the human experience is usually covered only at the end of a multiterm sequence of world history units has meant that it often ends

Bartleby the Scrivener by Herman Melville Essay Example For Students

Bartleby the Scrivener by Herman Melville Essay Herman Melvilles Bartleby the Scrivener is perhaps more relevant today than when he wrote it in 1853. Bartleby is the account of a talented young scrivener who possesses great talent and potential in his career of duplicating and composing documents. The tale takes us to the upscale Wall Street area of New York City, among the buildings and law offices of the city. The young Bartleby is thrown into the typical office drudgery associated with the type of employment he was seeking. The theme of the story questions why we do, what we do, when we go to work. Also the question of why do we feel certain things are just expected of oneself when we choose to enter employment. When Bartleby took the job of a scrivener it was understood that in addition to recording documents, one also is responsible for the editing and proofreading of their own and others work. However, Bartleby had different expectations for himself and his work. Bartlebys behavior questions all that is thought to be universal behavior while at work. Bartleby worked very hard, never taking breaks or even going home. These aspects of Bartleby were viewed as peculiar by his superior and coworkers, but were not undesirable traits. Bartleby also kept to himself most of the time, and did not get involved with office politics or affairs. Like many new employees, Bartleby had a small shared office near the boss so that he could be monitored. A comparison to life by todays office employees trapped in small cubicles could be made. The feeling of privacy is not there, and one could almost feel overwhelmed with only with their work and a small desk. These conditions may have weighed heavily on Bartleby, causing him to not feel very sociable with the others in the office. The life of drudgery as a scrivener grew weary on Bartleby. The odd behavior expressed by Bartleby continued until one day in a act of rebellion he said the words; I would prefer not to. He was referring to the request by his boss the edit his copy. The boss, shocked by this insubordinate behavior and politely asked again, and drew the same response from Bartleby; I would prefer not to. His boss assumed this was a temporary problem with Bartleby and assumed that it would pass in a day or so. His coworkers viewed his action as very odd, and even suggested as loony by one worker. His phrase now consumed every conversation he had with those in the office. His standard response to a request by someone in his office was; I would prefer not to. These words of defiance eventually led to Bartlebys dismissal from his job, and when asked to leave he refused to. This eventually led to his boss being forced to abandon his office in that building and move to another. His boss felt this would end all of his problems with Bartleby and he could go on with his life and business. However, Bartleby could not leave his mind. He was puzzled by the entire situation. The phrase, I would prefer not to., is not accepted in the workplace of then or today. It is understood that while we are at work certain things are expected of you, regardless of what you would rather do. When Bartleby spoke those words he went against all that is assumed by being employed. Bartleby carefully chose his words when being defiant. If he would have simply said no, it would be viewed as plain ignorance. However, the phrase; I would prefer not to. implies that he had put thought into his response and has reason to be defiant.

Integrated Marketing Communications for Battery - MyAssignmenthelp

Question: Discuss about theIntegrated Marketing Communications for Samsung Battery. Answer: Background of Task The Samsung battery crisis started in Australia due to which a number of people faced issues and difficulties (Essany, 2012). The battery time was too limited. In order to solve this issues, Samsung launched a campaign for recalling. The market share of Samsung declined significantly in Australia. For this purpose, Samsung launched an offer according to which it will replace, refund or repair all notes in Australia. However, this campaign did not provide significant results. The market of next innovative product of Samsung also impacted severely. In this report, a marketing campaign for solving this issues and regaining lost market share will be explained in detail. It will be highlighted that how new product can compensate this loss and regain the lost market share. Strategy Statement The name of this campaign is Next is State-of-the-art and marvelous. For purpose of regaining the lost market share and to handle the crisis of battery products, this campaign will be launched in Australia (Zurita, 2013). The strategy statement of this campaign is Whether it is an innovative product, an inspirational communication impression or an energizing style to unifying, we endeavor to support you [Australian Residents] make an obliging negotiation thats actually enhance collaboration. All we organize designed creatively to enable and stimulate you to make longer period communication with loved ones, and most essentially, to take advantage of technology by this technological advancement. Samsung Brand Positioning Samsung is collection of steeliness and expertise for new official, through its marvelous connection attributes and competitive design. The positioning statement of Samsun declares its distinction from other providers of mobile phones. In the domestic market of Australia where countless selection prosper, lustrous facade design of Samsung, escorted through its assortment of features of soft and hard, purify it a prime buying for the youth, scientifically modernized experts. The company struggles to shelter complete market of mobile and smartphones, is currently one of developing and growing global mobile corporations. In Australia, the company came up through innovative concepts to become additionally customer-oriented (Gillin, 2009). Source: https://www.labbrand.com/brandsource/issue-article/brand-positioning-strategies-rising-chinese-smartphone-brands The Samsung possesses exceptional marketing share. The above diagram indicates the brand positioning in detail. The company is providing innovative and differentiated products and services. Its core differentiating aspect is superior and rare designs. Objectives of the Message The core objective of this marketing campaign is to recapture the lost market share of Samsung in Australian market. The new commodity will offer exceptional battery timing along with diverse unique and remarkable features. This product will significantly fulfill the basic connectivity requirements of the target audience. The audience of this message will be provided an innovative product, an inspirational communication impression or an energizing style to unifying. The main outcome is to enhance and boost the communication and connectivity level of Australian people by providing enduring battery timing and innovative features. The core objective of this message is to recapture the lost market share and attract new target market (Bruner Anand 2000). Target Audience The target audience of this campaign will be professionals and experts people. ON the other hand, the residents of Australia are main target market of this campaign. According to geographic segmentation, Australia is targeted. According to demographic segmentation, all males and females are target audience. These individuals are highly qualified and business experts. According to psychographic segmentation, the people belong to upper and middle classes will be targeted. These individual pay more attention in quality and features as compared to price and cost. The excellence of commodity in each aspect is required such as designing, innovative features, availability of internet, long battery timing and connectivity features (Kim, 2013) Current Feelings of Target Audience Currently target market has negative feeling about the performance of Samsung mobiles after battery crisis. They think that next product of Samsung will be influenced negatively as well. In previous campaign, the company said that all affected customers will be compensated. However, target audience thinks that company cannot recover their loss and wastage of financed. However, it is expected that the feeling of Australian people will change and they will prefer this brand excellently. It is expected that company will recapture 15% market share by introducing this innovative products. It is expected that more than 20000 cases of new mobile phone will be sold in 1st year after inauguration (Dilger, 2015). Various Delivery Media Types The new commodity will be launched with an Integrated Marketing Communications campaign in Australia. This campaign might attract the customers who utilize smart phones as well as appreciate possessing the up-to-the-minute technology. The below mentioned advertising media tools will be used: Advertising In order to make brand consciousness, the TV advertisement is designed. The advertising agency of Samsung will launch new campaign in this year in Australia. The video ad shows how exhilarating and thrilling new product of Samsung is and its innovative features. The people can be seen in ads whose batteries of cell phones finish at most awful moments. Internet Marketing In this digital and globalized era, the successful results of a campaign cannot be achieved without online and internet marketing. The banners will be posted on pages of Facebook and YouTube. These are biggest and most essential social sites that provide exceptional marketing results. The ads will be posted on Facebook, Twitter, YouTube and website of the company (Ovide Wakabayashi 2015). Sales Promotions In order to appeal new target market, the persons who purchase an innovative Samsung phone will be provided a pack of bonus. On the other hand, the old mobiles with poor battery experience will be exchanged with new ones. 20% discount will be offered to first 1000 customers of new mobile. On returning old ones, the half price will be repaid by company (Campbell, 2015). Direct Marketing and PR Public relations are considered essential for promoting product. The celebrity endorsement will be used. A celebrity presenting new cellphone in front of millions of people is best. For direct marketing, the company will offer online and offline services. After sale services will be offered. The new product will be launched in a ceremony in which well-known celebrities and individuals will be invited. References Campbell, M. 2015. Samsung profits drop as mobile arm suffers 37.6% crash in Q2. AppleInsider. Retrieved from: https://appleinsider.com/articles/15/07/29/samsung-profits-drop-asmobile-arm-suffers-376-profit-crash-in-q2 Dilger, D.E. 2015. Samsung Mobile smartphone profits decline; unit sales to shrink for 2015. AppleInsider. Retrieved from: https://appleinsider.com/articles/15/10/29/samsung-mobilesmartphone-profits-decline-unit-sales-to-shrink-for-2015 Kim, M. 2013. Samsung's marketing splurge doesn't always bring bang-forbuck. Reuters. Retrieved from: https://www.reuters.com/article/us-samsung-marketingidUSBRE9AQ18720131127 Bruner, G. C. Anand, K. 2000. Web commercials and advertising hierarchy-of-effects. Journal of Advertising Research, 40 (1/2), p. 35-42 Gillin, P. 2009. Secrets of social media marketing: how to use online conversations and customer communities to turbo-charge your business. Fresno, CA: Quill Driver Books Essany, M. 2012. Target Touts Big 2013 focus on Mobile Marketing for Hispanic Community. Retrieved from: https://www.mobilemarketingwatch.com/target-toutsbig-2013-focus-on-mobile-marketing-for-hispaniccommunity-27662/ Zurita, A. 2013. Mobile Banking in Mexico: An Everyday Reality. Reach Hispanic. Retrieved from: https://reachhispanic.com/2013/08/13/mobile-banking-inmexico-an-everyday-reality/ Ovide, S., Wakabayashi, D. 2015. Apples share of smartphone industrys profits soars to 92%. The Wall Street Journal. Retrieved from: https://www.wsj.com/articles/apples-share-ofsmartphone-industrys-profits-soars-to-92-1436727458

Shakeema White Essays (842 words) - Theatre, Broadway Theatre

Shakeema White English II Summer 2017 Comparative Essay II Fences Play Vs Fences Movie Many times Screenwriters will buy right to a play to make a movie out of it in hopes of portraying the actual play. In 1985 an American playwright by the name of August Wilson had written a play called Fences. The play Fences explores the lives of African Americans and their race relations. The play first Broadway production was on March 26, 1987 directed by Lloyd Richards with cast that featured James Earl Jones as Troy, Mary Alice as Rose. In 1987 this play has won the Tony Award for best play and Pulitzer Prize for Drama . It was first developed at the Eugene O'Neill Theater Center's conference in 1983 and premiered at the Yale Repertory Theater in 1985. Wilson died in 2005 but he completed the play before his death. In 2016 Fences the award winning play became an American dram a film produced by Denzel Washington , which was the star of the drama film. The film was also produced by Todd Black and Scott Rudin. Production for drama film Fences began on April 25, 2016. It was then released on December 16, 2016. The movie grossed approximately $64 million and was choose as one of the top ten by the American Film Institute. It was also nominated for many awards with one of the starring actress Viola Davis winning an Oscar at the 89 th Academy Awards for Best Adapted screenplay and best actress. She also won a Golden Globe Award for best supporting actress for this film. The play and movie fences is about a black man named Troy that takes place over 6 to 7year period, who made a living in Pittsburg, PA as a sanitation worker in the 1950. He was a married to a woman named Rose and they had two sons together. One son is Corey who is a high school football player is from his and the other is a vagrant musician. He once had dreams in becoming a professional baseball player, which he thinks that he was robbed of because of his skin color, but the league told him that he was t old that he was too old to e nter the league at the time the league was accepting black a thletes. He was distraught over missing his opportunity of becoming a professional baseball player that it created animosity towards his family. This made him rebellious towards his son's dream in becoming a football player. He subdued his son's chances of meeting with a football recruiter. Differences: It is very hard to find much difference from the play and the movie fences because the producers of the drama film tried precisely make portray the film as the play was written. In the play there was a more faithful stage adaptation , where there is a consistency of the play taking place in one particular place being the front o f the house. Wilson only brought in a little of the outside world onstage. He only wanted to show only the importance of the dramatically events. In the movie scenes are filmed in various places. However, most of the movie takes place in the family's back yard that belongs to Maxson' s . The film is much less imaginative than Wilson's creation. However, Rose's part in the play did not expound into her history. She was the one that had to be the one to adapt and be the forgiving one, leaving the audience wanting to see more of her character. Even though August Wilson gave the less of a dialogue to the character Rose, the movie felt more of pain to adapt and to forgive. This led us to believe that she had more dialogue than what was actually written for her. There was a scene in the movie where Rose is having a conversation with her husband Troy where she says "I've been standing right here with you". This is where the audience got a feel her compassion. In the play this part was overseen and gave little feeling of what she was going through. It jumped right in to Troy and his

mandatory voting essays

mandatory voting essays Imagine a country where the voter turnout rate was one hundred percent. A country where all of the people of the nation came together to choose their future leaders. Unfortunately, this ideal is impossible without government intervention. Legislation should be created to enforce the act of mandatory voting in the United States. Making voting mandatory would give politicians an opportunity to be honest and truthful during their campaigns. Because they would not have a certain group of people to appease, candidates would be able to focus on issues they found significant. In doing this, the voters would have a clear image of what and who the candidate is. This in turn would make it easier to choose the right candidate for each individual person. Second, the population of our country would be better represented if everyone were forced to vote. Candidates would be compelled to focus on the issues of the entire race of Americans. For instance, it is true that highly educated white males are most likely to vote. In result, candidates make it their interest to please this group of people. Yet, if every person were forced to vote, representatives could center mainly on the classes that most populate the country or region in which they are running for. In order to force every citizen of the United States to vote a consequence must take place if someone chooses not to vote. This penalty should consist of a small fine less than $75. This would force most people to participate in the election of representatives, yet still not hurt a household if something should come up where an individual cannot vote. In order to bring out the honor and prosperity of America, it is imperative that the country unites and chooses their representatives. This is necessary because it will help our minority groups become better re ...

Global Marketing at AOL Case Study Example | Topics and Well Written Essays - 1000 words

Global Marketing at AOL - Case Study Example The success of any company is closely connected with its management team, a structure of the company and people work with it. The structure of AOL in Japan is not appropriate for the company of this type. The first problem is that only one person from eight, J. Barber, is involved in day-to-day operations. According to the report results, it is not enough for such a company as AOL because it needs more management control and adjustment on the upper level. The second problem is that the five groups report only to the President, who coordinates their work, but the other members of the board are unaware of the company's problems. The third and major problem is the unstable management team of the company (Hoecklin, 1995).During recent years 3 persons have held the office of the company but did not succeed. This is closely connected with the recruiting procedure used by AOL, who committed to his partner Mitsui this mission. Even if it was difficult to find top local people the company cou ld employ a US citizen on the President post. This experience is widely used by other companies in their foreign offices and proves its efficiency (for instance, the Coca-Cola company is used to appoint non-residents on the post of General Manager). The Barber should recommend to AOL to employ an experienced leader on the President's post (if the current will not be able to take AOL on the next level), and be involved in the process of staff selection itself (Griffith, Hu, Ryans, 2000).If AOL continues the present structure it will not gain any results in foreseeable future. Only a new radical strategic approach for management and the company's structure could take AOL on a higher level. The main impediments of AOL in Japan are that it employs the same marketing strategy that used in America. It uses bundling, magazines inserts and direct advertising, which cannot work on the Japanese market at all. And AOL did not take into account the difference that in Japan (in contrast to the U SA), the PC manufacturers are much more active in the ISP business.The overcome the obstacles AOL should use cultural approach to its marketing in Japan. Many problems associated with the relationships between people of different cultures stem from variations in norms and values. At its deepest level, however, culture comprises a set of basic assumptions that operate automatically to enable groups of people to solve the problems of daily life without thinking about them.